The NL5 series takes the best of two worlds; point scanners and spinning disc, leading to a system with options to do confocal, widefield or brightfield observations.

Phototoxicity is a central problem in the application of confocal microscopy for live cell imaging. To overcome these challenges, we developed the second generation of fast line-scanning confocal technologies. Using a line scanner instead of a point scanner, a confocal microscope provides high temporal resolution, at the same time reducing the phototoxicity and allowing long-term imaging. A slit pinhole, together with an extremely sensitive sCMOS camera as a detector, makes the NL5 series the perfect tool for fast and deep 3D live cell imaging.

The NL5+ is a confocal system which enables even faster imaging with cleaner results. This is a direct result of one of the new functionalities: its additional motorized filter wheel.

Our system uses a line scanner, instead of a point scanner confocal microscope. This provides high temporal resolution, while at the same time reducing phototoxicity. Since phototoxicity is one of the biggest challenges for researchers, this makes the NL5+ the perfect tool for live cell imaging.

You can also add the NL5+ to any widefield microscope. This will turn it into an advanced fast-scanning confocal imaging system.